6th Conference of the Mediterranean Neuroscience Society (MNS)
St Julian’s, Malta, 12-15 June 2017
President: Giuseppe Di Giovanni, Malta
Programme: link pdf
The 6th Edition of the Meeting of the Mediterranean Neuroscience Society (MNS) took place in St Julian’s, Malta, on June 12-25, 2017 with Prof. Giuseppe Di Giovanni as the President of the conference. This event was a great success, being the largest MNS conference since the beginning of the series. The 2017 MNS Meeting gathered 400 participants from 41 different countries, including Canada, USA and Australia, and offered a rich scientific program with 9 Plenary Lecturers, 67 selected contributed symposia, 9 keynote speakers and 4 Poster Sessions.
As detailed reported in the scientific program, in this meeting we had the pleasure of welcoming an exceptional lineup of Lecturers Keynote lectures: Giacomo Rizzolatti (University of Parma and University of Malta), Michaela Matteoli (University of Milan), Raphael Mechoulam (Hebrew University of Jerusalem), Pierre Magistretti (EPFL, Lausanne and KAUST, Saudi Arabia – IBRO president), Rosa Cossart (Aix-Marseille University – INSERM), Ilana Gozes (Tel Aviv University), Carmen Cavada (Autonomous University of Madrid) and Vincenzo Crunelli (University of Cardiff and University of Malta). An additional special lecture featured Juan Lerma (Neuroscience Inst. of Alicante, secretary general of the FENS). There was an exciting program, as it is shown by the conference proceedings and a relevant article with information on awards. A special round table on initiatives for euro-mediterranean cooperation was also held, featuring David Hansel (University Paris-Descartes) and Ahmed El Hady (Princeton University), as representatives of the training initiative Neurobridges, as well as a video-message by Mohammed Herzallah, leader of the Palestinian Neuroscience Initiative.
The topics of the Lectures witnessed the interdisciplinary nature of the meeting by encompassing Synaptic function, Mirror Neurons, Cellular and Network dynamics, Endocannabinoids, Neuroglia and neuronal plasticity, Catecholaminergic innervations in Parkinson’s Disease, and Neuropeptides in Neurodegenerative and Psychiatric disorders.
In line with the scientific interests of symposia organizers and invited speakers, many symposia were focused on the serotonin receptors and new therapeutics, mechanism and therapeutic relief for Tourette’s Syndrome, Drug addiction, circadian rhythms and network, Parkinson’s disease and Schizophrenia, Pain, Mental disorders, Neuroinflammation, Transcranial magnetic stimulation in addiction, Neurcytoskeleton functions in neurodegenerative and psychiatric diseases, Stress-related disorders, and Novel psychoactive substances are only a few examples. There was an exciting program, as shown by the conference proceedings and a relevant article with information on awards.
A special round table on initiatives for euro-Mediterranean cooperation was also held, featuring David Hansel (University Paris-Descartes) and Ahmed El Hady (Princeton University), as representatives of the training initiative Neurobridges, as well as a video-message by Mohammed Herzallah, leader of the Palestinian Neuroscience Initiative.
Guest Editoris: Liana Fattore, Marc Landry, Giuseppe Di Giovanni
Editorial link to https://www.sciencedirect.com/science/article/pii/S0165027018303625
This special issue of Journal of Neuroscience Methods comprises some of the works on new methodologies presented at the last Mediterranean Conference of Neuroscience that was organized in June 2017 in St. Julian’s, Malta. The MNS was created in 2009 by a group of Mediterranean neuroscientists willing to strengthen exchanges between countries of the Euro-Mediterranean region, promote education in Neuroscience and increase public awareness and sustain the Mediterranean Neuroscience Conference. The biennial meeting of the Mediterranean Neuroscience Society represents today a unique opportunity for scientists, clinicians and researchers from both the North and the South shores of the Mediterranean Sea to meet and present data from respective labs, discuss common projects of research and evaluate potential collaborations on shared fields of interest. Gathering more than 400 participants from over 30 different countries, including Canada, the USA, and Australia, MNS Meetings are not only important scientific events but also special social events, where science overlooks cultural differences.
Altogether, we believe that the articles presented in this Special Issue provide an important contribution to different methodologies to study the brain structure and neural networks in brain physiology and pathology. In June 2019, after six previous successful editions (Montpellier 1997; Marrakech 2006; Alexandria 2009; Istanbul 2012; Pula-Sardinia 2015; La Valletta-Malta 2017), the 7th edition of the meeting of the Mediterranean Neuroscience Society will take place in Marrakech (Morocco). We look forward to hosting you in one of the most vibrant cities in the Mediterranean. It will surely be a memorable experience.
Modelling motor neuron disease in fruit flies: Lessons from spinal muscular atrophy.
Beppe Aquilina, Ruben J. Cauchi. Pages 3-11.
Superparamagnetic iron oxide nanocolloids in MRI studies of neuroinflammation.
Lorenzo Ugga, Valeria Romeo, Enrico Tedeschi, Arturo Brunetti, Mario Quarantelli. Pages 12-23.
T-pattern detection and analysis for the discovery of hidden features of behaviour
M. Casarrubea, M.S. Magnusson, M.T. Anguera, G.K. Jonsson, ... G. Crescimanno. Pages 24-32.
Rat 50-kHz ultrasonic vocalizations as a tool in studying neurochemical mechanisms that regulate positive emotional states.
Nicola Simola, Stefan M. Brudzynski Pages 33-44.
A concise review of optical, physical and isotropic fractionator techniques in neuroscience studies, including recent developments.
Ömür Gülsüm Deniz, Gamze Altun, Arife Ahsen Kaplan, Kiymet Kübra Yurt, ... Suleyman Kaplan. Pages 45-53.
Pharmacology of epileptogenesis and related comorbidities in the WAG/Rij rat model of genetic absence epilepsy.
Emilio Russo, Rita Citraro. Pages 54-62.
Models and methods for conditioning the ischemic brain.
Antonio Vinciguerra, Ornella Cuomo, Pasquale Cepparulo, Serenella Anzilotti, ... Giuseppe Pignataro. Pages 63-74.
Animal models of early-stage Parkinson's disease and acute dopamine deficiency to study compensatory neurodegenerative mechanisms.
Laura Clara Grandi, Giuseppe Di Giovanni, Salvatore Galati. Pages 75-88.
Front cover: The cover image, by Radwa Khalil et al., is based on the Review Article Social Decision Making in Autism: On the impact of Mirror Neurons, Motor Control and Imitative Behaviors , DOI: https://doi.org/10.1111/cns.13001
The brain is unarguably the most complex and quite possibly the most fascinating organ in the body. It has inspired many generations of scientists to commit their own brain power to studying nervous system development, structure, and function. Unfortunately, the mysteries of the human nervous system defy easy exploration, but this has not deterred research in understanding neurological disease pathogenesis. The problem for health posed by brain disorders in the developed world and in many developing societies such as Mediterranean countries is demanding major important changes regarding the approach, efficiency, and solvency of governments, health systems, and the medical community. Research on brain function in health and disease is among the priorities of today's societies, and several indicators put the Mediterranean research area among strategic issues for the European Union (EU).
The Mediterranean Neuroscience Society (MNS) (https://mnsociety.live/), a member of IBRO, is highly active in this field and works toward three main objectives: (i) strengthening exchanges between Mediterranean neuroscientists from more developed countries in the world; (ii) promoting education in the neurosciences and increasing public awareness of progress in the field; (iii) sustaining scientific, training, and networking events, such as, in particular, the biennial Mediterranean Neuroscience Conference.
Many South–North collaborations and networks have emerged in recent years through bilateral and multi-lateral actions, supported by the EU or by international and national actions, whether for setting up teaching curricula (eg, Tempus programs), or building human potential (eg, FP7, H2020). Many other initiatives of cooperation (eg, Neurobridges) have seen the light of day, initiated by groups of motivated individuals who believe in the importance of scientific cooperation as a way to alleviate political distress between cultures.
The main pillar on which a government with an efficient health system has to stand on in dealing with brain disorders is a strong education system and research program with scientists motivated to understand the causes of the disease, implementing early diagnostic procedures, and discovering new and effective treatments to slow down the progression of the disease, thereby reducing disability and costs, and increasing the quality of life of the patients and their families. Currently, we are also in a favorable position to enter into two new areas of progress, such as prevention, relying on interesting new findings related to the molecular neuropathology and genetics of brain diseases, and also pharmacogenomics, as the most effective manner of optimizing drug development and therapeutics, increasing efficacy and safety, and reducing side-effects and unnecessary costs.
Social decision making in autism: On the impact of mirror neurons, motor control, and imitative behaviors
Radwa Khalil Richard Tindle Thomas Boraud Ahmed A. Moustafa Ahmed A. Karim Pages: 669-676
The Basal Ganglia: More than just a switching device
Tiziana Marilena Florio Eugenio Scarnati Ilaria Rosa Davide Di Censo Brigida Ranieri Annamaria Cimini Angelo Galante Marcello Alecci Pages: 677-684
System neuroscience: Past, present, and future
Giacomo Rizzolatti Maddalena Fabbri-Destro Fausto Caruana Pietro Avanzini Pages: 685-693
Modulation of forebrain function by nucleus incertus and relaxin-3/RXFP 3 signaling
Francisco E. Olucha-Bordonau Héctor Albert-Gascó Francisco Ros-Bernal Valeria Rytova Emma K. E. Ong-Pålsson Sherie Ma Ana M. Sánchez-Pérez Andrew L. Gundlach Pages: 694-702
Behavioral fragmentation in the D1CT -7 mouse model of Tourette's syndrome
Andrea Santangelo Marco Bortolato Laura J. Mosher Giuseppe Crescimanno Giuseppe Di Giovanni Emanuele Cassioli Valdo Ricca Maurizio Casarrubea Pages: 703-711
Activation of 5-HT 7 receptor by administration of its selective agonist, LP -211, modifies explorative-curiosity behavior in rats in two paradigms which differ in visuospatial parameters
Cristiana Carbone Annalisa Adinolfi Stefano Cinque Enza Lacivita Enrico Alleva Marcello Leopoldo Walter Adriani Pages: 712-720
Preferential modulation of the lateral habenula activity by serotonin-2A rather than -2C receptors: Electrophysiological and neuroanatomical evidence
Francis Delicata Cristiano Bombardi Massimo Pierucci Roberto Di Maio Philippe De Deurwaerdère Giuseppe Di Giovanni Pages: 721-733
Evaluation of cerebrospinal fluid phosphorylated tau231 as a biomarker in the differential diagnosis of Alzheimer's disease and vascular dementia
Spomenka Kiđemet-Piskač Mirjana Babić Leko Antonela Blažeković Lea Langer Horvat Nataša Klepac Zdenko Sonicki Danijela Kolenc Patrick R. Hof Marina Boban Ninoslav Mimica Fran Borovečki Goran Šimić Pages: 734-740
Does the Serotonin2C receptor segregate circuits of the basal ganglia responding to cingulate cortex stimulation?
Mélanie Lagière Marion Bosc Sara Whitestone Julien Manem Hasna Elboukhari Abdelhamid Benazzouz Giuseppe Di Giovanni Philippe De Deurwaerdère Pages: 741-744
Genetic rescue of absence seizures
Cian McCafferty William M. Connelly Roberta Celli Richard T. Ngomba Ferdinando Nicoletti Vincenzo Crunelli Pages: 745-758
President: Giuseppe Di Giovanni (Malta)
Honorary Presidents: Giacomo Rizzolatti (Italy/Malta) and Vincenzo Crunelli (UK/Malta)
PIs: Prof. Patrizia Campolongo & Dr. Maria Morena.
The lab has expertise in clinical and preclinical (rats) research on mechanisms of hypermemory and cognitive decline and related neurological disorder, such as Alzheimer’s Disease and on the influence of stress and arousal systems (including glucocorticoids, catecholamines and endocannabinoids) on learning and memory processes to elucidate mechanisms of stress-related psychiatric disorders at different developmental ages.
Postdocs are expected to work on the preclinical research part of the following funded projects: 1. “Leveraging the neural circuits of hypermemory to ameliorate memory dysfunction in prodromal Alzheimer's disease” 2. “Integrating cannabinoids into the treatment of Posttraumatic Stress Disorder: exploring mechanisms of amygdala-hippocampal communication during information contextualization” We encourage applications for well-motivated National or International Postdocs with:Background in neuropharmacology/neuroscience.Experience in all (or some) of the following techniques: behavioral pharmacology, electrophysiology (in vivo, ex vivo-whole cell patch clamp recordings), optogenetics, fiber photometry, stereotaxic surgery, immunohistochemistry, molecular biology.Experience in paper and grant writing.Good knowledge of English (spoken and written).Good networking ability. Contract length: One year (can be renewed for a further two years) Starting date: October/December2022
If interested, please send a motivation letter and a CV to email@example.com or firstname.lastname@example.org
Committee on Animals in Research in the Mediterranean Area (CARMA) Members of CARMA are the Councillors of MNS with the President as the Chairman
CARMA advises MNS on the responsible use of animals in neuroscience research, supports the development of relevant resources on animals in research and promotes public education in matters related to the use of animals in neuroscience in the Mediterranean area. "Animals are commonly used for scientific purposes in North Africa and the Middle East. However, this field is often inadequately regulated, with many countries lacking national legislation, policies, or guidelines for the care and use of animals used for research, testing, or education. This results in an essentially uncontrolled system where scientific quality and animal wellbeing cannot robustly be guaranteed, which may hinder acceptance (i.e., publication) of results by the scientific community and limit public confidence. An overarching system is needed to oversee the efficient promotion of scientific and ethical standards and the dissemination of information on laboratory animal science in North Africa and the Middle East, while each country should remain able to maintain a system of oversight that reflects its own cultures, traditions, religions, laws, and regulations." Mohr BJ, Fakoya FA, Hau J, Souilem O, Anestidou L. The Governance of Animal Care and Use for Scientific Purposes in Africa and the Middle East. ILAR J. 2016 May 1;57(3):333-346. doi: 10.1093/ilar/ilw035. PMID: 29117404.
The mission of CARMA falls within the following areas: Organizing the first Survey on Animals in Research in the Mediterranean AreaMonitoring and adviceEducation and outreachTraining and support
Dear MNS Member,
Thank you for your trust and support for the present Council.According to the results of the GA vote, the Council will remain as it is until MNS2023 when a new election will be called.Please find the results of the vote below,
We hope you will help us to make your Society better and to see you in
Giuseppe Di Giovanni
On behalf of the MNS Council